ICML

Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion. - Kuroda T, Kubori T, Uchida Y, Nagai H, Imada K Sci Rep (5) 10912 (2015)

Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion. - Kuroda T, Kubori T, Uchida Y, Nagai H, Imada K Sci Rep (5) 10912 (2015)

The 1,995,275-bp genome ofCoxiella burnetii, Nine Mile phase I RSA493, a highly virulent zoonotic pathogen and category B bioterrorism agent, was sequenced by the random shotgun method. This bacterium is an obligate intracellular acidophile that is highly adapted for life within the eukaryotic phagolysosome. Genome analysis revealed many genes with potential roles in adhesion, invasion, intracellular trafficking, host-cell modulation, and detoxification. A prev

The 1,995,275-bp genome ofCoxiella burnetii, Nine Mile phase I RSA493, a highly virulent zoonotic pathogen and category B bioterrorism agent, was sequenced by the random shotgun method. This bacterium is an obligate intracellular acidophile that is highly adapted for life within the eukaryotic phagolysosome. Genome analysis revealed many genes with potential roles in adhesion, invasion, intracellular trafficking, host-cell modulation, and detoxification. A prev

ABSTRACTGenetically distinct isolates ofCoxiella burnetii, the cause of human Q fever, display different phenotypes with respect to in vitro infectivity/cytopathology and pathogenicity for laboratory animals. Moreover, correlations betweenC. burnetiigenomic groups and human disease presentation (acute versus chronic) have been described, suggesting that isolates have distinct virulence characteristics. To prov

ABSTRACTGenetically distinct isolates ofCoxiella burnetii, the cause of human Q fever, display different phenotypes with respect to in vitro infectivity/cytopathology and pathogenicity for laboratory animals. Moreover, correlations betweenC. burnetiigenomic groups and human disease presentation (acute versus chronic) have been described, suggesting that isolates have distinct virulence characteristics. To prov