claude-mem github

I have a little hobby project I'm working on and I wanted to use the opportunity to fully make the switch to Positron from RStudio. I used Positron here and there when it first came out, but now that it's out of beta and has a more complete feature set (like remote SSH sessions!) I have everything I need to switch and not look back.

Reposted from the original at https://blog.stephenturner.us/p/positron-assistant-copilot-chat-agent I have a little hobby project I'm working on and I wanted to use the opportunity to fully make the switch to Positron from RStudio. I used Positron here and there when it first came out, but now that it's out of beta and has a more complete feature set (like remote SSH sessions!) I have everything I need to switch and not look back.

Protein-protein interactions (PPIs) are central to cellular functions, and predicting mutation-induced changes in binding affinity (ΔΔG) remains challenging. Although existing computational methods integrate sequence- and structure-derived features and thus implicitly capture certain sequence-structure relationships, they typically fuse these modalities through simple concatenation, without explicitly modeling their multidimensional and multiscale interdependencies.

Many state-of-the-art tools for sequence analysis are based on alignment-free techniques to manage high-throughput processing. Several routine tasks such as querying, indexing, and similarity search are based on k-mer statistics. In order to accommodate errors or mutations, spaced seeds have been increasingly used instead of