The aim of this study was to identify biological processes associated with neuroaxonal degeneration in multiple sclerosis (MS) by analyzing protein patterns linked to neurofilament light (NfL) protein in CSF and serum samples.
www.ncbi.nlm.nih.govCarbapenem-resistant Acinetobacter baumannii (CRAB) poses a threat to the treatment of infectious diseases. The efficacy of Origanum vulgare L. essential oil (OEO) and its primary components, carvacrol (CAR) and thymol (THY), against clinical CRAB isolates,was evaluated.
www.ncbi.nlm.nih.govFatigue is debilitating and costly for patients with Crohn's disease (CD) and the healthcare system. Thus, as there are no well-established therapies for fatigue in patients with CD, it is essential to investigate its risk factors and collaborate to prevent or reduce its burden.
www.ncbi.nlm.nih.govTo describe the frequency of opioid-induced neurotoxicity (OINT) after opioid conversion (OC) to methadone using the Stop-and-Go (SAG) method in cancer patients with inadequate pain control, and to identify factors associated with OINT.
www.ncbi.nlm.nih.govThe expression of augmenter of liver regeneration (ALR), a potent growth factor, is significantly up-regulated in hepatocellular carcinoma (HCC). This study aims to investigate the potential functions and mechanisms of ALR in HCC.
www.ncbi.nlm.nih.govThyrotropin-binding inhibitory immunoglobulin (TBII) is involved in the pathogenesis of Graves' orbitopathy (GO). Although thyroid-stimulating immunoglobulin (TSI) may offer superior diagnostic or prognostic value, its utility remains incompletely defined.
www.ncbi.nlm.nih.govFocal cortical dysplasia (FCD) is a prevalent cause of drug-resistant epilepsy, but a comprehensive understanding of its pathogenesis at a cellular resolution remains limited. Previous transcriptomic studies, often constrained by bulk tissue analysis, have been unable to dissect the cell-type-specific contributions to epileptogenesis.
www.ncbi.nlm.nih.govTo break through the performance bottlenecks of electromagnetic protection materials in terms of lightweight design, broadband absorption, and multifunctional integration, this work proposes a synergistic design strategy based on magneto-dielectric coupled absorbing units and periodic micro-circular array superstructures. At the microscopic scale, oleic acid (OA)-modified γ-Fe
www.ncbi.nlm.nih.govTo characterise patient and medication-related patterns observed in drug-related pressure ulcers (DRPUs) and provide descriptive findings that may support future consensus-building.
www.ncbi.nlm.nih.govWe previously showed that individuals without a prior history of asthma, presenting with unexplained respiratory symptoms and normal spirometry, may exhibit airway hyperresponsiveness and underlying eosinophilic (T2) inflammation, features suggestive of undiagnosed early-stage asthma. Improving our understanding of the inflammatory processes that contribute to asthma onset is essential, as it may ultimately lead to earlier detection, timely intervention and improved long-term outcomes.
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