英伟达ai课程

To examine the Indigenous Nourishment Scales (INS), a set of community-developed strengths-based measures of nourishment, for psychometric validity and reliability through community-based research with two urban American Indian/Alaska Native (AI/AN) communities.

To address the challenges of overflow metabolism and the heavy reliance on manual intervention in high-density

Rosamultin (RS), a triterpenoid compound, is the main active component of the traditional Dong ethnic medicine "Madeng'ai". It has been proven to have a significant therapeutic effect on improving renal fibrosis. However, the potential role of RS in the treatment of acute kidney injury (AKI) and the underlying molecular mechanisms remain unclear. Therefore, this study investigates whether RS confers renal protection in AKI and seeks to elucidate its underlying mechanisms.

The combination of non-steroidal mineralocorticoid receptor antagonists (nsMRAs) and sodium-glucose cotransporter-2 (SGLT2) inhibitors has shown renoprotective benefits in diabetic kidney disease; however, their synergistic effects in non-diabetic chronic kidney disease (CKD) remain underexplored. This study evaluated the efficacy and safety of finerenone combined with dapagliflozin versus dapagliflozin monotherapy in patients with non-diabetic CKD.

Histone deacetylase 8 (HDAC8) plays a role in glioblastoma progression, making it a promising therapeutic target. While HDAC8 inhibitors (HDAC8is) suppress glioblastoma growth and prolong survival in animal models, they do not eliminate HDAC8. In contrast, HDAC8-targeting proteolysis-targeting chimera (PROTAC), a selective HDAC8 degrader, induces proteasomal degradation of HDAC8 and thus eliminates all of its functions.