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Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS).

To compare the real-world safety profiles of α1-adrenoceptor antagonists (α1-blockers), 5α-reductase inhibitors (5ARIs), and phosphodiesterase type 5 inhibitor (PDE5I) used in the treatment of benign prostatic hyperplasia (BPH).
www.ncbi.nlm.nih.gov

The Novel HLA Class II Allele, HLA-DPA1*02:167, Identified by PacBio Sequencing.

The novel HLA-DPA1*02:167 allele, differs from HLA-DPA1*02:10, by one non-synonymous nucleotide substitution in exon 3, codon 96.
www.ncbi.nlm.nih.gov

Empathy as a predictive signal: why we devalue AI empathy.

People devalue empathic responses believed to be edited by artificial intelligence (AI). I propose that this reflects the role of empathy as a predictive social signal: genuine human empathy updates expectations about closeness and future commitment, a function that is weakened when empathy becomes cheap, automated, or outsourced.
www.ncbi.nlm.nih.gov